Initial symptoms are paresthesia or tingling at the bite site, followed by low-grade fever, lethargy, anxiety, agitation, and restlessness. Fear of wind and water, drinking water or hearing the sound of water can cause muscle spasms in the throat, difficulty swallowing, and painful symptoms, so rabies is also known as "hydrophobia". As the virus spreads in the central nervous system, it develops a fatal progressive inflammation of the brain and spinal cord. Then the following two situations may occur. Symptoms in manic rabies are hyperactivity, restlessness, fear of water, and sometimes wind. The patient died of cardiopulmonary failure a few days later. Patients should receive the vaccine as soon as possible and pay attention that each dose should be received as scheduled.
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